This is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed new volume, K. C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advances in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time. Develops domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis are systematically through the chosen synthesis Discusses the latest synthetic technologies in terms of mechanism and scope Includes new reactions, such as olefin metathesis, in mini-review style Abundant references for further reading CD with useful teaching material for lecturers is included with hardback version (ISBN 3-527-30685-4) Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis. From reviews of "Classics in Total Synthesis":"... a volume, (..) which any chemist with an interest in synthetic organic chemistry will wish to acquire." JACS"...this superb book (..) will be an essential purchase for many organic chemists." Nature

K.C. Nicolaou is Professor of Chemistry at the University of California, San Diego and is Chairman of the Department of Chemistry and holds the Skaggs Professorship of Chemical Biology and the Darlene Shiley Chair in Chemistry at The Scripps Research Institute Scott A. Snyder is the recipient of a Barry M. Goldwater Fellowship in Science and Engineering, a National Science Foundation Predoctoral Fellowship, and a Graduate Fellowship from Pfizer, Inc.