Dr. Khan's classic textbook on radiation oncology physics is now in its thoroughly revised and updated Fourth Edition. It provides the entire radiation therapy team--radiation oncologists, medical physicists, dosimetrists, and radiation therapists--with a thorough understanding of the physics and practical clinical applications of advanced radiation therapy technologies, including 3D-CRT, stereotactic radiotherapy, HDR, IMRT, IGRT, and proton beam therapy. These technologies are discussed along with the physical concepts underlying treatment planning, treatment delivery, and dosimetry. This Fourth Edition includes brand-new chapters on image-guided radiation therapy (IGRT) and proton beam therapy. Other chapters have been revised to incorporate the most recent developments in the field. This edition also features more than 100 full-color illustrations throughout. A companion Website will offer the fully searchable text and an image bank.

PART I: Basic Physics Chapter 1 Structure of Matter Chapter 2 Nuclear Transformations Chapter 3 Production of X-rays Chapter 4 Clinical Radiation Generators Chapter 5 Interactions of Ionizing Radiation Chapter 6 Measurement of Ionizing Radiation Chapter 7 Quality of X-ray Beams Chapter 8 Measurement of Absorbed Dose PART II: Classical Radiation Therapy Chapter 9 Dose Distribution and Scatter Analysis Chapter 10 A System of Dosimetric Calculations Chapter 11 Treatment Planning I: Isodose Distributions Chapter 12 Treatment Planning II: Patient Data, Corrections, and Setup Chapter 13 Treatment Planning III: Field Shaping, Skin Dose, and Field Separation Chapter 14 Electron Beam Therapy Chapter 15 Brachytherapy Chapter 16 Radiation Protection Chapter 17 Quality Assurance Chapter 18 Total Body Irradiation PART III: Modern Radiation Therapy Chapter 19 Three-Dimensional Conformal Radiation Therapy Chapter 20 Intensity-Modulated Radiation Therapy Chapter 21 Stereotactic Radiosurgery Chapter 22 High-Dose-Rate Brachytherapy Chapter 23 Prostate Implants Chapter 24 Intravascular Brachytherapy Chapter 25 Image-Guided Radiation Therapy Chapter 26 Proton Beam Therapy Appendix Index