Preface |
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ix | |
Contributors |
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xiii | |
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PART I General Principles of Pharmacology |
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Introduction to General Pharmacology |
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3 | (8) |
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Drug Solubility, Absorption, and Movement across Body Membranes |
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11 | (16) |
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27 | (7) |
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34 | (16) |
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Pharmacokinetics: Principles and Clinical Applications |
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50 | (12) |
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Drug Clearance by Specific Organs |
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62 | (6) |
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Dose-Response Relationships |
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68 | (7) |
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75 | (9) |
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Signal Transduction Systems |
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84 | (7) |
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Pharmacogenetics and Pharmacogenomics |
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91 | (16) |
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PART II Autonomic Nervous System and Neuromuscular Junction |
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Functional and Neurochemical Organization of the Autonomic Nervous System |
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107 | (14) |
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Cholinergic Agonists and Antagonists |
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121 | (16) |
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Adrenergic Receptor Agonists |
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137 | (19) |
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Adrenergic Receptor Antagonists |
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156 | (16) |
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Neuromuscular Transmission and Drugs (Muscle Relaxants) |
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172 | (15) |
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PART III Central Nervous System |
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Functional and Neurochemical Organization of the Central Nervous System |
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187 | (24) |
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Drugs That Modify Movement Control |
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211 | (12) |
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223 | (13) |
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Opioid Analgesics and Antagonists |
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236 | (16) |
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252 | (14) |
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266 | (9) |
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275 | (14) |
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Drugs Used for Anxiety, Stress Disorders, and Insomnia |
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289 | (14) |
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303 | (13) |
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Antidepressant and Mood-Stabilizing Agents |
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316 | (18) |
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Hallucinogens and Psychotomimetics |
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334 | (19) |
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PART IV Mediators and Modifiers of Tissue Responses |
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353 | (11) |
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Anti-inflammatory Analgesics |
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364 | (19) |
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383 | (12) |
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Histamine and Antihistamines |
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395 | (12) |
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PART V Cardiovascular System |
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Cardiovascular System Overview and Organization |
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407 | (15) |
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Digitalis Glycosides and Other Positive Inotropic Agents |
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422 | (8) |
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430 | (18) |
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Vasodilators and the Pharmacological Treatment of Hypertension |
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448 | (18) |
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Dyslipidemias and Antihyperlipidemic Drugs |
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466 | (19) |
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PART VI Respiratory, Renal, Blood, and Immune Systems |
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Drugs and the Respiratory System |
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485 | (8) |
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493 | (13) |
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Drugs That Affect Hemostasis |
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506 | (27) |
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Drugs (Agents) That Affect Erythropoiesis |
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533 | (12) |
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Immune System Organization, Modulation, and Pharmacology |
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545 | (12) |
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PART VII Gastrointestinal System |
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Pharmacotherapy of Acid-Peptic Disorders |
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557 | (15) |
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Pharmacotherapy of Intestinal Motility Disorders and Inflammatory Bowel Disease |
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572 | (12) |
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Drugs, Alcohol, and the Liver |
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584 | (19) |
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PART VIII Endocrine Systems |
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Vasopressin, Oxytocin, and Uterotonic Drugs |
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603 | (10) |
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Thyroid Hormones and Antihyperthyroid Drugs |
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613 | (7) |
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Gonadotropic and Gonadal Hormones |
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620 | (15) |
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Insulin and Other Anti-diabetic Drugs |
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635 | (12) |
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Adrenocortical Steroid Hormones |
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647 | (14) |
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PART IX Anti-infective and Anti-neoplastic Chemotherapy |
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Principles of Antimicrobial Therapy |
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661 | (9) |
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Antimicrobial Agents That Act on Microbial Cell Wall Formation |
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670 | (19) |
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Antimicrobial and Antifungal Agents That Act on Cell Membranes |
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689 | (8) |
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Antimicrobial Agents That Affect the Synthesis of Cellular Proteins |
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697 | (15) |
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Drugs That Affect Cellular Nucleic Acid Synthesis |
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712 | (12) |
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Chemotherapy of Common Parasitic Infections |
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724 | (15) |
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739 | (23) |
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Antiseptics, Disinfectants, and Sterilization |
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762 | (14) |
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776 | (21) |
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PART X Special Topics of Pharmacology |
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Sources of Individual Variation in Drug Response |
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797 | (6) |
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803 | (9) |
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812 | (11) |
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823 | (9) |
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Geriatric Clinical Pharmacology |
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832 | (9) |
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Vitamins and Other Micronutrients |
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841 | (27) |
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Herbal Preparations and Nutritional Supplements |
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868 | (10) |
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Drugs That Alter Bone Metabolism for the Treatment of Osteoporosis |
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878 | (12) |
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Drugs Used in Dermatology |
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890 | (10) |
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900 | (12) |
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912 | (19) |
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931 | (14) |
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Drug Abuse and Drug Dependence |
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945 | (14) |
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959 | (10) |
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Poisonings and Antidotal Therapy |
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969 | (10) |
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Index |
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979 | |