The Sugar Code Fundamentals of Glycosciences

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Edition: 1st
Format: Hardcover
Pub. Date: 2009-10-26
Publisher(s): Wiley-Blackwell
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Summary

This in-depth overview of the biochemistry of biologically relevant glycosylation of proteins as well as lipids is also one of the few books to cover their relevance in health and disease. Written by one of the pioneering experts in the field, and aimed at an intermediate level, this monograph is a perfect introduction to the topic for all students in life and medical sciences as well as biochemistry. In addition, it is equally intended for biomedical researchers and professionals who need to become familiar with the field.

Author Biography

Hans-Joachim Gabius obtained his Ph.D. in 1982 at the Max-Planck-Institute for Experimental Medicine in G+¦ttingen. After doing post-doctoral research from 1984-1985 in the group of S. H. Barondes at the UC San Diego, he was appointed first as assistant professor for biochemistry at the Max-Planck-Institute for Experimental Medicine in G+¦ttingen (1987) and then as associate professor for pharmaceutical chemistry at the University of Marburg (1991). Since 1993 he is heading the Institute for Physiological Chemistry, Faculty of Veterinary Medicine at the University of Munich. Prof. Gabius received numerous research awards including the Otto-Hahn-Medal (1983), the Award of the Dr. Carl-Duisberg-Foundation (1988) and the Award of the Paul-Martini-Foundation (1990). His research interests are focused on chemical, biophysical and biochemical analysis of protein - carbohydrate interactions with biomedical relevance, such as the development of glycoscientific strategies for tumor diagnosis and therapy and the elucidation of functions of mammalian lectins. His research led to a prominent placement in the ISI ranking of highly cited papers in 1998.

Table of Contents

Chemical Basis
The Biochemical Basis and Coding Capacity of the Sugar Code
Three-dimensional Aspects of the Sugar CodeKozar
The ChemistG+ s Way to Prepare Oligosaccharides
The ChemistG+ s Way to Prepare Multivalency
The Analysis of Protein-Bound Glycans
Natural Glycosylation - Glycoproteins N-Glycosylation
Glycosylation of Model and ""Lower"" Organisms
Table of Contents provided by Publisher. All Rights Reserved.

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