Thomas' Hematopoietic Cell Transplantation

by ; ; ;
Edition: 4th
Format: Hardcover
Pub. Date: 2009-04-13
Publisher(s): Wiley-Blackwell
List Price: $605.00

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Summary

This outstanding reference source on bone marrow transplantation has become recognised as the bible in the field. This fourth edition has been fully revised to reflect latest developments, and now features over 500 illustrations, including a colour plate section. The need for this new edition cannot be overstated - more than 13,000 new cases per year of haematopoietic stem cell transplantation have been reported to the International Bone Marrow Transplant RegistryThe original editor, Donnall Thomas, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases.The book also now includes a fully searchable CD with PDFs of the entire content.

Author Biography

Frederick R. Appelbaum, MD, Member and Director, Clinical Research Division, Fred Hutchinson Cancer Research Center; Professor and Head, Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA.

Stephen J. Forman, MD, Director, Department of Hematology and Bone Marrow Transplantation; Staff Physician, Division of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA.

Karl G. Blume, MD, Professor of Medicine, Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, Stanford, California, USA.

Robert S. Negrin, MD, Associate Professor of Medicine, Division of Bone Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

Table of Contents

1A History of Bone Marrow Transplantation
Uses and Growth of Hematopoietic Cell Transplantation
Overview of Hematopoietic Cell Transplantation Immunology
Histocompatibility
Functional Evolution of the Major Histocompatibility Complex
The Hematopoietic Microenvironment
Molecular Aspects of Stem Cell Renewal
Biology of Hematopoietic Stem and Progenitor Cells
Expansion of Hematopoietic Stem Cells
Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells
Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells
Pharmacological Basis for High-Dose Chemotherapy
Preparative Regimens and Modification of Regimen-Related Toxicities
Radiotherapeutic Principles of Hematopoietic Cell Transplantation
Radioimmunotherapy and Hematopoietic Cell Transplantation
Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation
T-Cell Depletion to Prevent Graft-vs.-Host Disease
Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation
Antibody Mediated Purging
Pharmacologic Purging of Bone Marrow
Molecular Inhibition of Gene Expression in Hematopoietic Cells
The Detection and Significance of Minimal Residual Disease
Pathology of Hematopoietic Cell Transplantation
Mechanisms of Tolerance
The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases
Murine Models for Graft-vs.-Host Disease
The Pathophysiology of Graft-vs.-Host Disease
Graft-versus-Tumor Responses
Adoptive Immunotherapy with Antigen-Specific T Cells
Autologous Graft-vs.-Host Disease
Biostatistical Methods in Hematopoietic Cell Transplantation
Outcomes Research in Hematopoietic Cell Transplantation
The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation
Clinical and Administrative Support for Hematopoietic Cell Transplant Programs
Nursing Issues in Hematopoietic Cell Transplantation
The PatientÆs Perspective
Ethical Issues in Hematopoietic Cell Transplantation
Psychosocial Issues in Hematopoietic Cell Transplantation
Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients, 507
Sexuality after Hematopoietic Cell Transplantation
Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation
Hematopoietic Cell Donors
Cord Blood Hematopoietic Cell Transplantation
In Utero Transplantation
Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy
Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation
Cryopreservation of Hematopoietic Cell
Recombinant Growth Factors after Hematopoietic Cell Transplantation
Hematopoietic Cell Donor Registries
Graft-vs.-Host Disease
Bacterial Infections
Fungal Infections after Hematopoietic Cell Transplantation
Cytomegalovirus Infection
Herpes Simplex Virus Infections
Varicella-Zoster Virus Infections
Epstein-Barr Virus Infection
Other Viral Infections after Hematopoietic Cell Transplantation
Gastrointestinal and Hepatic Complications
Neurological Complications of Hematopoietic Cell Transplantation
Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation
Principles of Transfusion Support before and after Hematopoietic Cell Transplantation
Immunological Reconstitution following Hematopoietic Cell Transplantation
Vaccination of Hematopoietic Cell Transplant Recipients
Pulmonary Complications after Hematopoietic Cell Transplantation
Nutritional Support of Hematopoietic Cell Recipients
Pain Management
Oral Complications
Growth and Development after Hematopoietic Cell Transplantation
Delayed Complications after Hematopoietic Cell Transplantation
Secondary Malignancies after Hematopoietic Cell Transplantation
Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia
Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria
Allogeneic Transplantation for Chronic Myeloid Leukemia
Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia
Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia
Allogeneic Transplantation for Acute Myeloid Leukemia in Children
Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults
Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children
Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders
Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma
Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia
Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors
Hematopoietic Cell Transplantation from Unrelated Donors
Management of Relapse after Allogeneic Transplantation
Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders
Allogeneic Hematopoietic Cell Transplantation for Solid Tumors
Autologous and Allogeneic Hematopoietic Cell Transplantation for HodgkinÆs Disease
Autologous Hematopoietic Cell Transplantation for Non-HodgkinÆs Lymphoma
Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia
Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia
Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia
Autologous Hematopoietic Cell Transplantation for Multiple Myeloma
Autologous Hematopoietic Cell Transplantation for AL Amyloidosis
Hematopoietic Cell Transplantation for Breast Cancer
Hematopoietic Cell Transplantation in Germ Cell Tumors
Hematopoietic Cell Transplantation in Ovarian Carcinoma
Hematopoietic Cell Transplantation for Neuroblastoma
Hematopoietic Cell Transplantation for Brain Tumors
Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors
AIDS and Hematopoietic Transplantation: HIV Infection, AIDS, Lymphoma and Gene Therapy
Hematopoietic Stem Cell Transplantation for Autoimmune Diseases
Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation
Marrow Transplantation in Thalassemia
Hematopoietic Cell Transplantation for Sickle Cell Disease
Hematopoietic Cell Transplantation for Immunodeficiency Diseases
Hematopoietic Cell Transplantation for Osteopetrosis
Hematopoietic Cell Transplantation for Storage Diseases
Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders
Hematopoietic Cell Transplantation for Fanconi Anemia
Hematopoietic Cell Transplantation in the 21st Century
Ernest Beutler
Table of Contents provided by Publisher. All Rights Reserved.

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