Chiral Separations and Stereochemical Elucidation Fundamentals, Methods, and Applications

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Edition: 1st
Format: Hardcover
Pub. Date: 2023-04-04
Publisher(s): Wiley
List Price: $266.66

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Summary

The book covers three main concepts: the fundamentals of chiral separation, the most applied chiral selectors, and stereochemical elucidation methods – presenting the most recent research on chiral separations and stereochemical elucidation. Part I focuses on different chiral separation methods including gas chromatography, supercritical fluid chromatography, capillary electrophoresis, and chromatographic enantioseparation. Part II looks at historical developments, mechanism of recognition, and applications of chiral selectors. Part III describes different methods for stereochemical elucidation including X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, electronic circular dichroism and more.

Author Biography

Quezia B. Cass, PhD, is a full Professor in the Chemistry Department of Federal University of São Carlos in Brazil.

Maria Elizabeth Tiritan, PhD, is an Assistant Professor of Organic Chemistry at the Faculty of Pharmacy of Porto University in Portugal.

Juliana Cristina Barreiro, PhD, is a researcher at Chemistry Institute of São Carlos, University of São Paulo, in São Carlos, University of São Paulo , Brazil.

João Marcos Batista Jr., PhD, is an Assistant Professor of Chemistry at the Federal University of São Paulo - UNIFESP, in São José dos Campos, Brazil.

Table of Contents

List of Contributors

               Preface

 

 

Chapter 1            Chiral separation by LC

 

Chapter 2            Chiral separation by GC

 

Chapter 3            Chiral separation by supercritical fluid chromatography

Chapter 4            Chiral separation by capillary electrophoresis and capillary electrophoresis – mass spectrometry: fundamentals, recent developments and applications

Chapter 5            Chiral Separations at Semi and Preparative Scale

Chapter 6            Polysaccharides

Chapter 7            Macrocyclic antibiotics and Cyclofructans

Chapter 8            Cyclodextrins

Chapter 9            Pirkle type

Chapter 10          Proteins

Chapter 11          Chiral stationary phases derived from cinchona alkaloids

Chapter 12          X-ray crystallography for stereochemical elucidation

Chapter 13          NMR for stereochemical elucidation

Chapter 14          Absolute configuration from chiroptical spectroscopy

 

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