The book covers three main concepts: the fundamentals of chiral separation, the most applied chiral selectors, and stereochemical elucidation methods – presenting the most recent research on chiral separations and stereochemical elucidation. Part I focuses on different chiral separation methods including gas chromatography, supercritical fluid chromatography, capillary electrophoresis, and chromatographic enantioseparation. Part II looks at historical developments, mechanism of recognition, and applications of chiral selectors. Part III describes different methods for stereochemical elucidation including X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, electronic circular dichroism and more.
Chiral Separations and Stereochemical Elucidation Fundamentals, Methods, and Applications
by Cass, Quezia Bezerra; Tiritan, Maria Elizabeth; Batista Junior, Joã o Marcos; Barreiro, Juliana CristinaBuy New
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Summary
Author Biography
Quezia B. Cass, PhD, is a full Professor in the Chemistry Department of Federal University of São Carlos in Brazil.
Maria Elizabeth Tiritan, PhD, is an Assistant Professor of Organic Chemistry at the Faculty of Pharmacy of Porto University in Portugal.
Juliana Cristina Barreiro, PhD, is a researcher at Chemistry Institute of São Carlos, University of São Paulo, in São Carlos, University of São Paulo , Brazil.
João Marcos Batista Jr., PhD, is an Assistant Professor of Chemistry at the Federal University of São Paulo - UNIFESP, in São José dos Campos, Brazil.
Table of Contents
List of Contributors
Preface
Chapter 1 Chiral separation by LC
Chapter 2 Chiral separation by GC
Chapter 3 Chiral separation by supercritical fluid chromatography
Chapter 4 Chiral separation by capillary electrophoresis and capillary electrophoresis – mass spectrometry: fundamentals, recent developments and applications
Chapter 5 Chiral Separations at Semi and Preparative Scale
Chapter 6 Polysaccharides
Chapter 7 Macrocyclic antibiotics and Cyclofructans
Chapter 8 Cyclodextrins
Chapter 9 Pirkle type
Chapter 10 Proteins
Chapter 11 Chiral stationary phases derived from cinchona alkaloids
Chapter 12 X-ray crystallography for stereochemical elucidation
Chapter 13 NMR for stereochemical elucidation
Chapter 14 Absolute configuration from chiroptical spectroscopy
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